eradicate
To completely get rid of something so it never returns.
To eradicate means to completely destroy or eliminate something, leaving no trace of it behind. When scientists work to eradicate a disease like smallpox, they don't just reduce the number of cases: they work to make it disappear entirely from the planet. Farmers eradicate weeds from their fields, doctors eradicate infections from patients' bodies, and communities work together to eradicate problems like hunger or illiteracy.
Eradicating something means pulling it out by the roots so it can't grow back. If you just mow dandelions, they'll return next week. But if you eradicate them by digging out every root, they're gone for good.
Scientists actually succeeded in eradicating smallpox in 1980 through a massive worldwide vaccination effort. It was one of humanity's greatest achievements: a deadly disease that had killed millions simply ceased to exist in nature. Today, researchers hope to eradicate other diseases like polio and malaria. When you eradicate something, you don't just solve the problem temporarily. You solve it permanently.