Frame has several related meanings that all involve creating boundaries or structure around something:

When you frame a picture, you put a border around it to protect it and make it stand out on the wall. The wooden or metal border itself is called the frame. Buildings have frames too: the skeleton of beams and supports that holds everything up before the walls go on.

Your body has a frame as well. When someone talks about a person's frame, they mean their basic build or structure: tall or short, broad-shouldered or slight. You might hear someone described as having a “large frame” or a “delicate frame.”

The word also means to present or express something in a particular way. A student might frame an argument carefully to persuade their teacher, or a lawyer might frame a question to get a specific answer. How you frame something affects how others understand it. The same situation can look completely different depending on how it's framed: losing a game could be framed as “we failed” or “we learned what to practice next.”

Less commonly, to frame someone means to make them look guilty of something they didn't do by creating false evidence. In mystery stories, the real criminal sometimes tries to frame an innocent person for a crime.